Perceptions of cannabis health information labels among people who use cannabis in the U.S. and Canada

• 8,729 respondents who used cannabis were asked to evaluate six labels A label about dependence was the least well known driving stoned rated most likely change behavior Respondents more frequently less receptive from locations where recreational use legal aware of harms The emergence industries poses a new public health challenge. Health information are part strategy for tobacco and alcohol, but there is limited research on cannabis-related messaging. This study explored perceptions among people in last 12 months residing U.S. Canada. Global Drug Survey (GDS) large anonymous cross-sectional web-survey. In GDS2019, presented with (dependence; stoned; smoking; developing brain; lack motivation; effects memory), if new, believed, would it behavior, acceptability having products. paper includes 1,275 Canada 2,224 states at time survey, 5,230 other states. Few said that (6.6-24.6%). Most believable (63.5-72.0%) than message (28.1% 56.8% believed), which perceived be (10.2%). Driving (58.5%). living say messages those compared daily lower (27.8%) using 1-48 days (40.6%). Novel, may effective changing behavior. Regular consumers susceptible messages. Information focusing safer strategies benefits reducing acceptable should assessed future research.